Ng TCD parameters PI was found to become correlated with SjO2. There was a leak correlation amongst PI and SjO2, for SjO2 values under 75 (r = ?.51, P < 0.01). A breakpoint SjOvalue of 75 was demonstrated above which there was no correlation between PI and SjO2 (r = ?.59, P > 0.05). Using the very same strategy Vmax and Vmin have been unable to provide more information and facts. Conclusion: The pulsatility index (PI) can’t predict adjustments of SjO2 values. For that reason a combination of TCD and SjO2 monitoring can deliver improved access to cerebral hemodynamics.PIntracranial pressure monitoring in two district basic hospital ICUsJJ Paddle Intensive Care Unit, Royal Cornwall Hospital, Truro TR1 3LJ, UK There’s a growing consensus that, in selected sufferers, intracranial pressure (ICP) monitoring is definitely an proper purchase 12α-Fumitremorgin C intervention in district general hospitals. It improves outcome in individuals with traumatic brain injury [1] and is secure [2]. In the Southwest area two district general hospitals devoid of on-site neurosurgical facilities have already been inserting Camino fibreoptic transducers in their ICUs given that 1997. I carried out a retrospective case note audit of ICP monitored patients in the two centres. Fifty-one patients had monitors inserted in between six October 1997 and 28 February 2001. Data had been collected on: sex, age, initial Glasgow coma score (GCS), diagnosis, duration of ICP monitoring and incidence and nature of complications. Sixty-nine percent of individuals had been male, using a median age of 29 (range 1?1 years). Median GCS was six and 76 had an initial GCS of 8 or much less. By far the most popular indication for ICP monitoring was traumatic brain injury (72 ). Other diagnoses had been anoxic coma (12 ), meningitis (8 ), subarachnoid haemorrhage (4 ), intracerebral bleed (two ) and encephalitis (two ). Median duration of monitoring was three days. Only two individuals were monitored for more than 5 days; both these individuals received two monitors. The complication price was low. One particular (2 ) patient had a minor scalp haemorrhage. A single (two ) patient had a compact intracerebral haemorrhage, detected as an incidental discovering on CT scan; it had no clinical sequelae. 1 (2 ) monitor developed a fault and had to become resited. No infectious complications were observed. The information from this audit adds to the weight of evidence that PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20724831 ICP monitoring in chosen patient groups is safe in district general hospitals.This implies that the cytokines could possibly be a good indicator for the course of CSF infections and hence anCritical CareVol six Suppl22nd International Symposium on Intensive Care and Emergency Medicineindicator for the optimal timing for shunt re-implantation. CSF leucocyte count and its differentiation will depend on the examiner and on the good quality of cell preparation. As a result the quantitative determination in the cytokines is additional objective. Regrettably, the cytokinevalues are very variable, which means that only trends can be estimated. Additional studies are required for dependable data concerning the CSF infection status.PPropofol attenuates the neuroprotective effects of magnesium in experimental traumatic brain injuryD Aktan*, T Erden*, M Kaya, N kar*, L Telci*, F Esen* *University of Istanbul Health-related Faculty Department of Anesthesiology Reanimation, and University of Istanbul Healthcare Faculty Division of Physiology, Capa Istanbul, Turkey Objectives: Propofol can be a preferred nonbarbiturate anesthetic agent. Its neuroprotective effects are controversial. The neuroprotective effects of magnesium salts have been documented. We ai.