T 2008, 21(4):243-255. 15. Van Regenmortel MHV: Mapping Epitope DL-Tryptophan MedChemExpress structure and Activity: From One-Dimensional Prediction to Four-Dimensional Description of Antigenic Specificity. Procedures 1996, 9(3):465-472. 16. Kulkarni-Kale U, Bhosle S, Kolaskar AS: CEP: a conformational epitope prediction server. AG-494 In Vivo Nucleic Acids Res 2005, 33(Web Server):W168-171. 17. Haste Andersen P, Nielsen M, Lund O: Prediction of residues in discontinuous B-cell epitopes making use of protein 3D structures. Protein Sci 2006, 15(11):2558-2567. 18. Moreau V, Fleury C, Piquer D, Nguyen C, Novali N, Villard S, Laune D, Granier C, Molina F: PEPOP: computational design of immunogenic peptides. BMC Bioinformatics 2008, 9:71. 19. Ponomarenko J, Bui HH, Li W, Fusseder N, Bourne PE, Sette A, Peters B: ElliPro: a brand new structure-based tool for the prediction of antibody epitopes. BMC Bioinformatics 2008, 9:514. 20. Sweredoski MJ, Baldi P: PEPITO: improved discontinuous B-cell epitope prediction using multiple distance thresholds and half sphere exposure. Bioinformatics 2008, 24(12):1459-1460. 21. Sun J, Wu D, Xu T, Wang X, Xu X, Tao L, Li YX, Cao ZW: SEPPA: a computational server for spatial epitope prediction of protein antigens. Nucleic Acids Res 2009, 37(Web Server):W612-616. 22. Moreau V, Granier C, Villard S, Laune D, Molina F: Discontinuous epitope prediction primarily based on mimotope evaluation. Bioinformatics 2006, 22(9):1088-1095. 23. Bublil EM, Freund NT, Mayrose I, Penn O, Roitburd-Berman A, Rubinstein ND, Pupko T, Gershoni JM: Stepwise prediction of conformational discontinuous B-cell epitopes applying the Mapitope algorithm. Proteins 2007, 68(1):294-304. 24. Huang YX, Bao YL, Guo SY, Wang Y, Zhou CG, Li YX: Pep-3D-Search: a approach for B-cell epitope prediction primarily based on mimotope evaluation. BMC Bioinformatics 2008, 9:538. 25. Dougherty DA: Cation-pi interactions in chemistry and biology: a brand new view of benzene, Phe, Tyr, and Trp. Science 1996, 271(5246):163-168.26. Novotny J, Bruccoleri RE, Saul FA: On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.three, and HyHEL-5. Biochemistry 1989, 28(11):4735-4749. 27. Lu H, Skolnick J: A distance-dependent atomic knowledge-based possible for enhanced protein structure choice. Proteins 2001, 44(3):223-232. 28. Wiederstein M, Sippl MJ: ProSA-web: interactive net service for the recognition of errors in three-dimensional structures of proteins. Nucleic Acids Res 2007, 35(Net Server):W407-410. 29. Chen J, Liu H, Yang J, Chou KC: Prediction of linear B-cell epitopes making use of amino acid pair antigenicity scale. Amino Acids 2007, 33(three):423-428. 30. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Information Bank. Nucleic Acids Res 2000, 28(1):235-242. 31. Connolly ML: Solvent-accessible surfaces of proteins and nucleic acids. Science 1983, 221(4612):709-713. 32. Allcorn LC, Martin AC: SACS elf-maintaining database of antibody crystal structure info. Bioinformatics 2002, 18(1):175-181. 33. Lee B, Richards FM: The interpretation of protein structures: estimation of static accessibility. J Mol Biol 1971, 55(3):379-400. 34. Richards FM: Regions, volumes, packing and protein structure. Annu Rev Biophys Bioeng 1977, 6:151-176. 35. Chou WI, Pai TW, Liu SH, Hsiung BK, Chang MD: The loved ones 21 carbohydrate-binding module of glucoamylase from Rhizopus oryzae consists of two internet sites playing distinct roles in ligand binding. Biochem J 2006, 396(3):469-477. 36. Jiang Y, Lee A, Chen J, Ruta V, Ca.
