Ash severity than placebo.42 Ziaei et al. studied the effects of vitamin E on menopausal hot flashes.43 They reported that vitamin E and placebo each reduced hot flashes, but there was a considerable difference involving them with regards to reducing hot flashseverity score and hot flash frequency. These outcomes have been consistent together with the results on the present study. ErbB3/HER3 Storage & Stability Loprinzi et al. studied the effects of venlafaxine with distinct dosages during four weeks on 221 females with breast cancer.44 They reported a reduction in hot flash severity scores of 31 to 61 versus 27 in placebo, and a reduction in hot flash frequency of 30 to 58 versus 19 in placebo. The effects of Scitalopram compared with placebo in treating hot flash in 205 women was studied by Freeman et al.45 They discovered that Scitalopram was more productive in minimizing hot flash severity just after eight weeks when compared with placebo. Stearns et al. Studied the effects of paroxetine inside the therapy of hot flash.46 A 62.two lower was observed in hot flash with paroxetine using the dosage of 12.five mg plus a 64.four lower together with the dosage of 25 mg immediately after six weeks of treatment, plus a 37.8 decrease by placebo. The imply each day hot flash frequency with a dosage of 12.five mg decreased from 7.1 to three.8, with a dosage of 25 mg it decreased from six.four to 3.3, and in placebo from six.6 to 4.eight. An additional study around the effects of venlafaxine on hot flash of ladies triggered by breast cancer was conducted by Carpenter et al.47 This study indicated that venlafaxine was additional helpful than placebo. Gordon et al. also reported that sertraline was additional efficient in minimizing hot flashes in 102 ladies with menopause when compared with placebo.48The results of these studies are comparable for the present research which is because of their comparable mechanism. Having said that, the outcomes from the study by Grady et al. indicated that sertraline was not successful around the frequency and severity of perimenopausal and postmenopausal hot flashes.49 SuvantoLuukkonen et al. cond-ucted a randomized clinical trial during 9 months on the effects of citalopram and fluoxetine on hot flashes in 150 menopausal females. They reported that there was no substantial difference involving the groups with regards to hot flash frequency.50 CCR8 site Bouchard et al. studied the effects ofJournal of Caring Sciences, Jun 2013; two (2), 131-140|Copyright 2013 by Tabriz University of Health-related SciencesBani et al.desvenlafaxine on vasomotor symptoms, in 35 regions of Europe, two regions of South Africa, and one region of Mexico.51 In week 12 no important distinction was observed in the reduction of imply frequency of each day hot flashes involving the groups. In the present study folic acid had no unwanted effects; as a result, it could be used for minimizing hot flashes and improving the women’s quality of life. Considering the fact that there are a limited number of studies around the impact of folic acid on menopausal hot flash, further studies on this matter are advisable.ConclusionThe results on the present study indicated that folic acid and placebo were each effective in the improvement of hot flash. However, folic acid was extra helpful. Folic acid is really a safe, reasonably priced, and acceptable medication for ladies; as a result, it may be regarded as an option method for relieving menopausal hot flashes.Ethical issuesNone to be declared.Conflict of interestThe authors declare no conflict of interest within this study.AcknowledgmentsOur appreciation goes towards the analysis deputy of Tabriz University of Medical Sciences for the economic assistance,.
