Product Name :
PIK-75 hydrochloride
Description:
PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models.
CAS:
372196-77-5
Molecular Weight:
488.74
Formula:
C16H15BrClN5O4S
Chemical Name:
N’-[(1E)-6-bromoimidazo[1,2-a]pyridin-3-ylmethylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide hydrochloride
Smiles :
Cl.CN(/N=C/C1=CN=C2C=CC(Br)=CN12)S(=O)(=O)C1=CC(=CC=C1C)[N+]([O-])=O
InChiKey:
VOUDEIAYNKZQKM-MYHMWQFYSA-N
InChi :
InChI=1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Pyocyanin site
Shelf Life:
≥360 days if stored properly.Loxapine GPCR/G Protein
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM.PMID:32250713 In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models.|Product information|CAS Number: 372196-77-5|Molecular Weight: 488.74|Formula: C16H15BrClN5O4S|Synonym:|PIK-75 Hydrochloride|Chemical Name: N’-[(1E)-6-bromoimidazo[1,2-a]pyridin-3-ylmethylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide hydrochloride|Smiles: Cl.CN(/N=C/C1=CN=C2C=CC(Br)=CN12)S(=O)(=O)C1=CC(=CC=C1C)[N+]([O-])=O|InChiKey: VOUDEIAYNKZQKM-MYHMWQFYSA-N|InChi: InChI=1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
