G reactive oxygen species and ERK inactivation. J Cell Biochem 2012, 113:473?85. 13. Kyaw M, BLU-554 price Yoshizumi M, Tsuchiya K, Kirima K, Tamaki T: Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells. Hypertens Res 2001, 24:251?61. 14. Staedler D, Idrizi E, Kenzaoui BH, Juillerat-Jeanneret L: Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells. Cancer Chemother Pharmacol 2011, 68:1161?172. 15. Kaiserova H, Simunek T, van der Vijgh WJ, Bast A, Kvasnickova E: Flavonoids as protectors against doxorubicin cardiotoxicity: role of iron chelation, antioxidant activity and inhibition of carbonyl reductase. Biochim Biophys Acta 2007, 1772:1065?074. 16. Zhou J, Liang S, Fang L, Chen L, Tang M, Xu Y, Fu A, Yang J, Wei Y: Quantitative proteomic analysis of HepG2 cells treated with quercetin suggests IQGAP1 involved in quercetin-induced regulation of cell proliferation and migration. OMICS 2009, 13:93?03. 17. Aalinkeel R, Bindukumar B, Reynolds JL, Sykes DE, Mahajan SD, Chadha KC, Schwartz SA: The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90. Prostate 2008, 68:1773?789.18. Timms JF, Cramer R: Difference gel electrophoresis. Proteomics 2008, 8:4886?897. 19. Lin ST, Chou HC, Chang SJ, Chen YW, Lyu PC, Wang WC, Chang MD, Chan HL: Proteomic analysis of proteins responsible for the development of doxorubicin resistance in human uterine cancer cells. J Proteomics 2012, 75:5822?847. 20. Hung PH, Chen YW, Cheng KC, Chou HC, Lyu PC, Lu YC, Lee YR, Wu CT, Chan HL: Plasma proteomic analysis of the critical limb ischemia markers in diabetic patients with hemodialysis. Mol Biosyst 2011, 7:1990?998. 21. Lin CP, Chen YW, Liu WH, Chou HC, Chang YP, Lin ST, Li JM, Jian SF, Lee YR, Chan HL: Proteomic identification of plasma biomarkers in uterine leiomyoma. Mol Biosyst 2011, 8:1136?145. 22. Chen YW, Liu JY, Lin ST, Li JM, Huang SH, Chen JY, Wu JY, Kuo CC, Wu CL, Lu YC, et al: Proteomic analysis of gemcitabine-induced drug resistance in pancreatic cancer cells. Mol Biosyst 2011, 7:3065?074. 23. Wu CL, Chou HC, Cheng CS, Li JM, Lin ST, Chen YW, Chan HL: Proteomic analysis of UVB-induced protein expression- and redox-dependent changes in skin fibroblasts using lysine- and cysteine-labeling two-dimensional difference gel electrophoresis. J Proteomics 2012, 75:1991?014. 24. Lai TC, Chou HC, Chen YW, Lee TR, Chan HT, Shen HH, Lee WT, Lin ST, Lu YC, Wu CL, et al: Secretomic and proteomic analysis of potential breast cancer markers by two-dimensional differential gel electrophoresis. J Proteome Res 2010, 9:1302?322. 25. Chou HC, Lu YC, Cheng CS, PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27321907 Chen YW, Lyu PC, Lin CW, Timms JF, Chan HL: Proteomic and redox-proteomic analysis of berberine-induced cytotoxicity in breast cancer cells. J Proteomics 2012, 75:3158?176. 26. Mokni M, Hamlaoui-Guesmi S, Amri M, Marzouki L, Limam F, Aouani E: Grape seed and skin extract protects against acute chemotherapy toxicity induced by doxorubicin in rat heart. Cardiovasc Toxicol 2012, 12:158?65. 27. Calvo-Romero JM, Fernandez-Soria-Pantoja R, Arrebola-Garcia JD, Gil-Cubero M: Ischemic heart disease associated with vincristine and doxorubicin chemotherapy. Ann Pharmacother 2001, 35:1403?405. 28. Chen JY, Chan HL, Chou HC: Proteomic analysis of quercetin-induced cardioprotective effects. Genomic Med, Biomarkers, and Health Sci 2012, 4:51?3. 2.
