F axis, whereas whereas an asterisk more than the whisker of a group indicates a substantial difference of that group are Figure 2. Concentrations of per liter ( oles/L) and plotted around the right axis.to low concentraexpressed in micromoles total proteins and albumin in serum of with the manage group in accordance with pigs exposed The plot illustrates Dunn’s post-test.the tions of ZEN (ZENlow; n = ten), high doses of ZEN (ZENhigh; n = ten), and control (n = ten). Total median (line inside box); 25th and 75th percentiles (box); 1.5 occasions the inter-quartile distance proteins are expressed in grams per ). Asterisks more than on the left axis, whereas of significance (Tukey; whiskers); and outliers ( ,liter (g/L) and plotted a bar indicate the levelalbumin values of are expressed in micromoles per liter ( oles/L) whisker of a the correct axis. The plot illustrates Kruskal allis test, whereas an asterisk more than the and plotted ongroup indicates a important differthe that group within box); 25th and 75th percentiles (box); post-test. ence ofmedian (linewith the manage group based on Dunn’s1.5 occasions the inter-quartile distance (Tukey; whiskers); and outliers ( , ). Asterisks more than a bar indicate the amount of significance ofKruskal allis test, whereas an asterisk more than the whisker of a group indicates a significant differ-g/L2.1.2. Lipid MetabolismToxins 2021, 13,Exposure to ZEN had a significant effect on biochemical Safranin custom synthesis parameters connected with of 16 4 lipid metabolism (Figure three). At day 7, substantial variations in low-density (LDL), highdensity lipoprotein (HDL), and cholesterol (CHO) levels (p = 0.0032, 0.003, and 0.0033, two.1.2. Lipid Concentrations of all 3 parameters were larger in respectively) have been observed. Metabolism Exposure to ZEN had ZENlow group compared to controls as well as a considerable effect on biochemical parameters connected signifiZENhigh pigs, but variations had been not with lipid metabolism (Figure 3). At day 7, important variations in low-density (LDL), high-density cant in accordance with Dunn’s post-test. No cholesterol (CHO) levels (p = 0.0032, 0.003, and inside the respectively) lipoprotein (HDL), and significant differences were identified 0.0033, levels of absolutely free fatty acids (FFA) have been observed. Concentrations of all 3 parameters have been higher in ZENlow conat this time-point. Pinacidil Description Slightly reduce levels of HDL, LDL, and CHO group in comparison with controls and ZENhigh pigs, but differences had been not substantial according centrations have been observed in pigs exposed to ZEN when compared with controls at day 21, altto Dunn’s post-test. No important variations were discovered in the levels of free fatty acids hough variations have been not significant, except for the ZENhigh group in comparison with handle (FFA) at this time-point. Slightly decrease levels of HDL, LDL, and CHO concentrations have been observed turn, substantially decrease levels of day 21, even though differences on for HDL (p-value 0.05). Inin pigs exposed to ZEN when compared with controls at FFA were quantified were not important, except for 0.001). Dunn’s post-test was for HDL (p-value FFA animals exposed for 21 days to ZEN (p the ZENhigh group compared to controlsignificant for 0.05). In turn, drastically reduce levels of FFA had been quantified on animals exposed for 21 days concentrations in ZENlow and ZENhigh groups compared to controlconcentrations in ZENlow and to ZEN (p 0.001). Dunn’s post-test was considerable for FFA (p 0.01 and p 0.001, ZENhigh groups when compared with handle (p 0.01 and p 0.001, respectively). respectively).Fig.
