Age (years) 80 112 134 Pubertal status1 Peri-pubertal Pubertal Serum Leptin (ng/mL) 5 5 85 15 Physical Activity (METS)2 17 176 260 40 60 60 57 65 518.eight 494.1 510.2 487.1 167.two 198.9 181.9 158.3 0.74 34 36 26 31 59 64 60 59 483.7 534.8 480.5 507.four 169.5 200.9 166.1 162.1 0.28 17 30 39 41 141 one hundred 503.two 500.7 191.9 152.four 0.91 84 43 168 53 21 501.3 523.eight 454.five 181.four 167.9 149.0 0.31 90 25 12 48 63 53 51 495.four 517.1 524.five 469.4 159.0 180.9 219.2 145.5 0.53 28 32 27 26 1 one hundred 81 25 8 444.7 503.six 509.4 489.7 472.5 . 198.four 170.five 135.0 166.6 0.99 0 47 48 15 3 85 123 34 506.1 508.4 469.8 198.7 169.7 135.7 0.51 48 63 16 98 114 30 523.7 492.four 468.9 188.4 172.7 140.8 0.24 48 59Females (N = 132) N Imply SD P NMales (N = 118) Mean SD PMeanSDP500.5 499.3 473.151.three 167.1 152.0.50 55546.1 484.9 459.217.4 179.7 121.0.494.4 497.7 492.174.eight 153.6 128.0.37 60521.4 519.6 450.227.5 185.eight 142.0.. 496.three 506.1 490.three 501.. 159.2 174.8 125.0 200.0.1 53 33 10444.7 510.1 514.3 488.9 455.. 229.0 166.six 155.7 165.0.486.7 479.9 528.eight 508.125.5 157.four 203.0 154.0.20 31 26507.7 555.six 520.1 428.199.6 197.six 239.0 125.0.498.six 517.1 429.157.9 165.5 137.0.78 28504.four 529.7 487.206.2 172.9 165.0.500.3 486.165.5 143.0.57507.four 511.226.7 159.0.475.7 524.1 466.9 510.183.2 144.three 143.7 169.0.42 34 21486.9 544.3 505.six 499.165.8 242.0 202.8 148.0.548.6 482.five 476.4 469.176.four 161.four 131.4 146.0.26 24 31479.8 511.6 538.7 503.148.six 247.5 213.four 168.0.ABR: BMI, physique mass index; 1 Sex-specific peri-pubertal (1) and pubertal (1) status had been determined by physician-assessed Tanner staging for males (genital or pubic hair improvement) and females (breast or pubic hair development; 2 METs are metabolic equivalent.MRS amongst the entire sample and stratified by offspring sex are presented in Table 4. We didn’t observe any considerable associations within the unadjusted models. Having said that, immediately after adjustment to get a priori covariates and sex-stratification, we found an inverse association in between trimester twoprenatal urinary BPA and MRS in male offspring. To illustrate, just about every 1-unit increase in ln-transformed trimester two maternal urinary BPA was marginally linked with a 72.eight ( = 0.728; p 0.ten) decrease in adolescent male MRS. Benefits also revealed that exposure to MDSFrontiers in Nutritionfrontiersin.orgZamora et al../fnut..TABLEDistribution of exposure variables from prenatal and adolescent exposure periods.N Urinary BPA (ng/mL), SG-adjustedMaternal measures Trimester a single Trimester two Trimester 3 Adolescent measures 198 200 225GMGSDMin255075Max1.AGRP Protein web 6 1.Irisin Protein custom synthesis 7 1.PMID:28440459 three 1.two.two two.1 two.0 2.0.2 0.2 0.3 0.0.9 1.0 0.8 0.1.five 1.5 1.1 1.2.8 two.5 1.8 two.23.four 30.three 23.4 27.N Mediterranean eating plan score (0)Maternal measures Trimester one Trimester two Trimester 3 Adolescent measures 227 234 235MeanSDMin255075Max4.7 four.7 4.eight three.1.five 1.5 1.six 1.two.0 1.0 0.0 0.four.0 four.0 four.0 3.five.0 five.0 5.0 4.six.0 6.0 six.0 5.eight.0 eight.0 eight.0 eight.ABR: BPA, Bisphenol A; SG, Distinct gravity; GM, Geometric mean; GSD, Geometric standard deviation; Min: minimum, 25 : 25th percentile; 50 : 50th percentile; 75 : 75th percentile; Max: maximum.TABLEPercent alterations in adolescent MRS per -unit enhance in ln-transformed prenatal maternal urinary BPA.Trimester of exposureAdolescent metabolic syndrome danger score Model 1: Unadjusted N BPA MDS BPAMDS N Model two: A priori covariates BPA MDS BPAMDSEntire sample Trimester one particular Trimester two Trimester three Females Trimester one particular Trimester two Trimester 3 Males Trimester one Trimester two Trimester three 90 90 107 0.174 -0.043.
