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March 9, 2017Updated March 9, 2017

Finally, we assayed apoptosis-related molecules to determine whether the protective effect of 7,8-DHF on cortical neurons was also mediated through apoptosis inhibition

GTPase atpase

1 min read

TrkB phosphorylation was found largely in neurons all around the influence web site, but...

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March 8, 2017Updated March 8, 2017

The expression of neurons with high ASK1-ir may reflect constitutive `injury/remodeling’ levels such as that seen with basal expression levels of ATF3

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2 min read

The expression of neurons with higher ASK1-ir may mirror constitutive `injury/remodeling’ ranges such as...

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March 7, 2017Updated March 7, 2017

Animal treatments including anesthesia, euthanasia and administration were carried out in accordance with the Principle of Laboratory Animal Care

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Prenatal exposure of VPA or PBS was carried out as earlier documented . Rats...

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March 6, 2017Updated March 6, 2017

Until recently, it was believed that all three isoforms functioned to increase tumor cell survival and proliferation making Akt an attractive therapeutic target

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Till not too long ago, it was thought that all 3 isoforms functioned to...

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March 3, 2017Updated March 3, 2017

While the GABAergic and glutamatergic pathways were altered in a region- and developmental-specific manner

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Our outcomes (Figure six) display that a continual oral treatment method with tiagabine hydrochloride...

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March 2, 2017Updated March 2, 2017

Expression of both transgenes is regulated by neural-specific elements of the mouse Thy1 promoter to drive overexpression in the brain

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2 min read

Expression of each transgenes is controlled by neural-distinct components of the mouse Thy1 promoter...

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March 1, 2017Updated March 1, 2017

To determine the intracellular distribution of Myo9b in osteoclasts, cells were labeled by immunocytochemistry and examined by confocal microscopy

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Osteoclasts specific multiple myosin isoforms ( and our unpublished knowledge), and to determine...

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February 28, 2017Updated February 28, 2017

In other studies, FA acid supplementation has been reported to improve endothelial dysfunction in hyperhomocysteinemia (HHcy) patients with vascular disease

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1 min read

In addition, FA supplementation mitigated the impact of ADMA on NO synthesis and also...

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February 27, 2017Updated February 27, 2017

Using extracts of dissected cerebral cortex and hippocampus, these workers reported that phosphorylation of PDK1 in the KO mouse

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WT mouse mind of PDK1 and a number of other proteins in the insulin...

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February 24, 2017Updated February 24, 2017

To assess whether HO-1 expression was increased consequently to an endoplasmic reticulum-stress response

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The pro-apoptotic element endoplasmic reticulum pressure-induced transcription issue C/EBP homologous protein (CHOP) was lowered...