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December 30, 2016Updated December 30, 2016

In addition, nutlin-3a induced p21 expression, an important mediator of p53dependent cell cycle arrest, 24 h after incubation, and it persisted 96 hours after treatment

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As revealed in Figure 1E, U87MG cells showed a time-dependent increase of apoptosis induced...

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December 29, 2016Updated December 29, 2016

In this report, we used the HGF/c-MET ligand-receptor interaction as a model for the development of a ligand-receptor proximity assay as a method to measure receptor activation in FFPE specimens

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In this report, we used the HGF/c-Met ligand-receptor conversation as a product for the...

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December 28, 2016Updated December 28, 2016

Concomitantly, to determine if the increase in cell numbers observed through the combination of PTH plus Flt-3L was due to alterations in cell apoptosis

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Concomitantly, to establish if the enhance in cell numbers observed via the mixture of...

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December 27, 2016Updated December 27, 2016

Briefly, the sorted TIP-1 positive or -negative cells were cultured on glass coverslips at 37uC for 24 hours

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Again the cells were washed and Annexin V-APC (BD Biosciences, Franklin Lakes, NJ) was...

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December 26, 2016Updated December 26, 2016

The identification of precursor cells in the adult nervous system raises the possibility that clinical benefit may be achieved via their activation

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The identification of precursor cells in the grownup nervous program raises the probability that...

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December 23, 2016Updated December 23, 2016

The spleen will be exteriorized through the incision, and a splenectomy will be performed by placing ligatures around the splenic vasculature and removing the spleen

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Briefly, the viral titer was decided by transducing 3T3 cells with supernatant (additionally polybrene,...

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December 22, 2016Updated December 22, 2016

As shown in figure 1A, Ser-9 phosphorylation of GSK3b (p-GSK3b) was indeed decreased in MKK7-JNK2-transfected HKE293T cells

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As proven in determine 1A, Ser-9 phosphorylation of GSK3b (p-GSK3b) was certainly lowered in...

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December 21, 2016Updated December 21, 2016

In addition to the up-regulated genes, the analysis shows some remarkable, high fold-change values for down-regulated genes

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In addition to the up-controlled genes, the evaluation displays some outstanding, large fold-adjust values...

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December 20, 2016Updated December 20, 2016

The transcriptional activity of Neurog1 was monitored using a co-transfected 3xE-Box-Luc or a NeuroD2-Luc reporter

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The cortices have been sliced into three hundred mm sections and cultured ex vivo....

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December 19, 2016Updated December 19, 2016

In the small seeds from crosses between wild type ovules and pollen from met1-3/+ plants, embryo growth was relatively normal as compared to the endosperm

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In the tiny seeds from crosses between wild sort ovules and pollen from met1-3/+...