from unique directions, they perform a really
evolutionary conserved, which tends to make them essential pharmacological targets. In any case, nucleotides...
This implies that the enzyme element in the enzyme/substrate complicated
imating the calculated Kmapparent (see Experimental Procedures). The inhibitory action of 3 was extremely...
Hence, compounds four? ended up preferred for additional optimization.
Reversion of the carboxamide group at the four-posture of the piperidinyl ring of 4?...